Toxicity Evaluation of Anacardium occidentale, the Potential Aphrodisiac Herb

Table 14

Values of clinical chemistry parameters of female rat orally administered with the leaf extract of A. occidentale for 90 days. Values were as mean±SEM (N=15/group).

Blood Chemistry	Reference values	Vehicle	AO 20 mg/kgBW	AO 100 mg/kgBW	AO 500 mg/kgBW
BUN(mg/dL)	11.7-25	22.68±0.59	22.69±0.65	21.66±0.59	22.77±0.46
Creatinine(ml/ dL)	0.3-0.6	0.48±0.02	0.49±0.02	0.49±0.02	0.54±0.03
Cholesterol(ml/ dL)	23-97	54.20±4.67	52.47±2.51	55.73±2.98	58.73±2.77
Triglyceride(ml/ dL)	16-175	62.00±6.51	52.13±4.54	74.00±4.84	64.67±5.36
ALT(U/L)	14-64	141.80±6.16	139.93±5.10	142.64±7.16	142.29±6.79
AST(U/L)	64-222	35.67±2.71	43.80±3.88	39.00±2.36	44.80±5.76
ALP(U/L)	18-62	51.67±7.28	60.33±6.92	62.20±3.43	93.33±32.99
Total Bilirubin(mg/ dL)	0.07-0.21	0.11±0.007	0.12±0.014	0.1±0.001	0.1±0.001

Alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase