Rs2015 Polymorphism in miRNA Target Site of Sirtuin2 Gene Is Associated with the Risk of Parkinson’s Disease in Chinese Han Population

Table 2

Frequency distribution of nine SNPs of SIRT1 and SIRT2 gene in PD patients and healthy controls.

Gene	SNP	Genotype	Allele	Dominant model		Recessive model
		P-value	P-value	P-value	95%CI	P-value	95%CI
SIRT1	rs3740051 G>A	0.0967	0.7481	0.6176	0.7381-1.667	0.0591	0.9504 - 5.346
SIRT1	rs2273773 C>T	0.1363	0.8568	0.0948	0.8729 - 4.670	0.1456	0.4919 - 1.111
SIRT1	rs7069102 G>C	0.4880	0.7627	0.5260	0.5312 - 1.382	0.5294	0.1484 - 2.291
SIRT1	rs12778366 C>T	0.0459	0.0111	0.1670	0.0999 - 1.328	0.0221	1.0760- 2.668
SIRT1	rs4746720 C>T	0.7823	0.7894	0.9012	0.6640 - 1.592	0.5460	0.7092 - 1.914
SIRT1	rs7895833 G>A	0.7928	0.7939	1.159	0.7724 - 1.741	0.5360	0.2646 - 1.086
SIRT2	rs2015 G>T	0.0431	0.4590	0.4155	0.7529 - 1.987	0.0436	1.0120 - 2.599
SIRT2	rs10410544 C>T	0.3097	0.3173	N.A	N.A	N.A	N.A
SIRT2	rs45592833 G>T	0.7928	0.7939	N.A	N.A	N.A	N.A