miR-451 Silencing Inhibited Doxorubicin Exposure-Induced Cardiotoxicity in Mice

Figure 1

miR-451 inhibition prevented Dox-induced cardiac injury. (a) The level of miR-451 in the hearts (n=5). (b) The level of miR-451 in the H9c2 cells (n=5). (c) The level of miR-451 in the hearts (n=5). (d) Body weight in the Dox-treated mice (n=10). (e) The ratio of heart weight to tibial length in the indicated mice (n=10). (f) The level of NT-proBNP in the hearts (n=6). (g) The level of cardiac cTnI after Dox treatment (n=6). (h) The level of CK in the mice (n=6). P<0.05 compared with the group with saline or PBS. ^#P<0.05 compared with mice after Dox injection.

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