miR-451 Silencing Inhibited Doxorubicin Exposure-Induced Cardiotoxicity in Mice

Figure 2

miR-451 inhibition improved cardiac function in mice. (a-b) The alteration in +dP/dt and –dP/dt in mice (n=8). (c) Ejection fraction in the mice (n=8). (d-e) Cardiac output and stroke work in the mice (n=8). (f-g) Tau (Weiss and Glantz) in the mice (n=8). P<0.05 compared with the group with saline. ^#P<0.05 compared with mice after Dox injection.

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