miR-451 Silencing Inhibited Doxorubicin Exposure-Induced Cardiotoxicity in Mice

Figure 3

miR-451 inhibition improved cardiomyocyte contractile properties. (a) Resting cell length. (b) Peak shortening (normalized to cell length). (c-d) Maximal velocity of shortening (+dL/dt) and maximal velocity of relengthening (−dL/dt). P<0.05 compared with the group with saline. ^#P<0.05 compared with mice after Dox injection. n=50 cells from 3 mice per group.

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