Hub Genes and Key Pathway Identification in Colorectal Cancer Based on Bioinformatic Analysis

Table 2

The overall survival and disease-free survival analyses of each key gene were performed using clinical data from GSE87211 or TCGA database. value <  0.05.

MCODE	Gene symbol	Overall survival in GSE87211 ( value)	Overall survival in TCGA ( value)	Disease-free survival in TCGA ( value)
1	CXCL11	0.48	0.54	0.0045
1	SSTR1	0.58	0.54	0.73
1	SSTR2	0.44	0.74	0.48
1	CXCL12	0.32	0.68	0.46
1	HCAR3	0.92	0.85	0.78
1	SST	0.42	0.75	0.94
1	APLN	0.38	0.4	0.26
1	CXCL8	0.81	0.05	0.41
1	CXCR2	0.42	0.56	0.57
1	PPY	0.61	NA	NA
1	NPY	0.39	0.31	0.12
1	PPBP	0.59	0.22	0.084
1	SAA1	0.41	0.98	0.53
1	PMCH	0.42	0.6	0.17
1	GAL	0.67	0.23	0.83
1	CXCR1	0.94	0.46	0.77
1	NPY1R	0.74	0.71	0.75
1	CCL23	0.44	0.79	0.98
1	CXCL6	0.42	0.44	0.35
1	CCL28	0.62	0.37	0.9
1	FPR2	0.57	0.45	0.87
1	CXCL1	0.2	0.13	0.34
1	CXCL2	0.064	0.042	0.49
1	CXCL3	0.26	0.047	0.46
1	HTR1D	0.71	0.19	0.096
1	GALR1	0.69	NA	NA
1	CNR1	0.82	1	0.27
1	AGT	0.89	0.073	0.11
1	FPR1	0.48	0.59	0.89
1	PTGDR2	0.81	0.015	0.36
1	CCR8	0.55	0.37	0.7
1	INSL5	0.87	NA	NA
2	F2RL2	0.39	0.16	0.97
2	GCG	0.51	0.056	0.38
2	GRP	0.7	0.039	0.28
2	OXTR	0.75	0.17	0.65
2	GPR4	0.51	0.65	0.4
2	NPSR1	0.15	0.22	0.73
2	UTS2B	0.15	0.63	0.88
2	PROK2	0.87	0.61	0.98
2	AGTR1	0.82	0.05	0.032
2	EDN3	0.89	0.064	0.46
2	CHRM1	0.82	0.23	0.33