Development and Validation of a Novel Model to Predict Liver Histopathology in Patients with Chronic Hepatitis B

Figure 1

Flow diagram of the study design and recruitment of study subjects. Patients with chronic HBV infection (n=467) from the First Hospital of Quanzhou (n=137, Quanzhou, China) and Huashan Hospital (n=330, Shanghai, China) were evaluated. A total of 258 patients with liver biopsy at baseline were included in this study. Histologic grading of necroinflammation (G) and staging of liver fibrosis (S) were performed according to the Scheuer scoring system.