Exosomes in Cancer: Circulating Immune-Related Biomarkers

Figure 2

An illustration presents the profiles of exosomes derived from dendritic cells (DEXs). These exosomes may be immunostimulatory. DEXs were found to possess a variety of surface membrane proteins, which could potentially stimulate CD8+ and CD4+ T cells; allow for effective targeting and docking to recipient cells; which are postulated to participate in exosome/acceptor cell interactions, or activate NK (Natural Killer) cells leading to cytokine regulation and immunoglobulin synthesis (26, modif.).