Correlations of Expression Levels of a Panel of Genes (IRF5, STAT4, TNFSF4, MECP2, and TLR7) and Cytokine Levels (IL-2, IL-6, IL-10, IL-12, IFN-γ, and TNF-α) with Systemic Lupus Erythematosus Outcomes in Jordanian Patients

<div>mRNA levels of SLE genes. mRNA expression levels were determined by semiquantitative RT-PCR using the IQ5 cycler: (a) IRF5, (b) TLR7, (c) MECP2 (α), (d) MECP2 (β), (e) STAT4 (α), (f) STAT4 (β), and (g) TNFSF4 in PBMCs from SLE patients (N = 51) and healthy controls (N = 50) after normalization with GAPDH mRNA level. Data were analyzed by the Mann–Whitney test. Each symbol represents an individual sample, and horizontal lines indicate median values and 25 and 75 percentiles.</div>

BioMed Research International

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Figure 1

Figure 1: Correlations of Expression Levels of a Panel of Genes (IRF5, STAT4, TNFSF4, MECP2, and TLR7) and Cytokine Levels (IL-2, IL-6, IL-10, IL-12, IFN-γ, and TNF-α) with Systemic Lupus Erythematosus Outcomes in Jordanian Patients

Figure 1 | Correlations of Expression Levels of a Panel of Genes (IRF5, STAT4, TNFSF4, MECP2, and TLR7) and Cytokine Levels (IL-2, IL-6, IL-10, IL-12, IFN-γ, and TNF-α) with Systemic Lupus Erythematosus Outcomes in Jordanian Patients 