Research Article

Combination of Fresh Frozen Plasma and Cryosupernatant Plasma for Therapeutic Plasma Exchange in Thrombotic Thrombocytopenic Purpura: A Single Institution Experience

Table 1

Demographic and clinicopathological characteristics of the enrolled patients.

CharacterCP dominantFFP dominantP value

Number1116
FFP/CP ratio0.0015
Age(years)0.53
Gender1.00
 male58
 female68
PLASMIC score0.39
 510
 6811
 725
Bentley score0.43
 20-3088
 >3038
Platelet count (×109/L)0.95
Uncorrected reticulocyte (%)0.49
MCV (fL)0.67
INR0.04
Creatinine (μmol/L)0.38
Indirect bilirubin (μmol/L)0.58
Active cancer1(9.09%)1(6.25%)1.00
D-dimer (ug/ml)0.96
Procedures to complete response0.04
Time to complete response (days)0.04
Steroid use (%)11(100%)16(100%)1.00
Vincristine use (%)1(9.09%)0(0%)0.41
Cyclophosphamide use (%)3(27.27%)6(37.5%)0.69
IVIg use (%)4(36.36%)10(62.5%)0.25
Rituximab use (%)1((9.09%)2(12.5%)1.00

IVIg: intravenous immunoglobulin; MCV: mean corpuscular volume; INR: international normalized ratio.