BioMed Research International

Research Article

Expression Profiling of Exosomal miRNAs Derived from the Peripheral Blood of Kidney Recipients with DGF Using High-Throughput Sequencing

Table 3

Exosomal miRNAs identified in the peripheral blood of kidney recipients.


miRNA name	Length	Sequence	Group	Expression level	Common/specific

hsa-let-7a-5p	22	TGAGGTAGTAGGTTGTATAGTT	gp1a	high	DGF specific
hsa-let-7b-5p	22	TGAGGTAGTAGGTTGTGTGGTT	gp1a	high	common
hsa-let-7d-5p	22	AGAGGTAGTAGGTTGCATAGTT	gp1a	high	DGF specific
hsa-let-7f-5p	22	TGAGGTAGTAGATTGTATAGTT	gp1a	high	DGF specific
hsa-let-7g-5p	22	TGAGGTAGTAGTTTGTACAGTT	gp1a	high	DGF specific
hsa-let-7i-5p_R-1	21	TGAGGTAGTAGTTTGTGCTGT	gp1a	high	common
hsa-miR-100-5p_R-1	21	AACCCGTAGATCCGAACTTGT	gp1a	middle	DGF specific
hsa-miR-101-3p_R+1	22	TACAGTACTGTGATAACTGAAG	gp1a	high	common
hsa-miR-103a-3p_R-2	21	AGCAGCATTGTACAGGGCTAT	gp1a	high	common
hsa-miR-106a-5p_1ss1AC	23	CAAAGTGCTTACAGTGCAGGTAG	gp1a	high	DGF specific
hsa-miR-106b-5p_R-1	20	TAAAGTGCTGACAGTGCAGA	gp1a	high	common
hsa-miR-107_R-2	21	AGCAGCATTGTACAGGGCTAT	gp1a	high	common
hsa-miR-10b-5p_R-1	22	TACCCTGTAGAACCGAATTTGT	gp1a	middle	DGF specific
hsa-miR-125b-5p	22	TCCCTGAGACCCTAACTTGTGA	gp1a	high	DGF specific
hsa-miR-126-3p	22	TCGTACCGTGAGTAATAATGCG	gp1a	high	common
hsa-miR-126-5p	21	CATTATTACTTTTGGTACGCG	gp1a	high	DGF specific
hsa-miR-128-3p	21	TCACAGTGAACCGGTCTCTTT	gp1a	middle	DGF specific
hsa-miR-142-3p_L-1	22	GTAGTGTTTCCTACTTTATGGA	gp1a	high	DGF specific
hsa-miR-142-5p_L+2R-3	20	CCCATAAAGTAGAAAGCACT	gp1a	high	DGF specific
hsa-miR-143-3p_R+1	22	TGAGATGAAGCACTGTAGCTCT	gp1a	high	DGF specific
hsa-miR-144-3p_R-1	19	TACAGTATAGATGATGTAC	gp1a	high	common
hsa-miR-145-5p	23	GTCCAGTTTTCCCAGGAATCCCT	gp1a	middle	DGF specific
hsa-miR-146a-5p	22	TGAGAACTGAATTCCATGGGTT	gp1a	middle	DGF specific
hsa-miR-148a-3p	22	TCAGTGCACTACAGAACTTTGT	gp1a	high	DGF specific
hsa-miR-148b-3p	22	TCAGTGCATCACAGAACTTTGT	gp1a	middle	DGF specific
hsa-miR-150-5p	22	TCTCCCAACCCTTGTACCAGTG	gp1a	middle	DGF specific
hsa-miR-151a-5p	21	TCGAGGAGCTCACAGTCTAGT	gp1a	middle	DGF specific
hsa-miR-152-3p	21	TCAGTGCATGACAGAACTTGG	gp1a	middle	DGF specific
hsa-miR-15a-5p_R-1	21	TAGCAGCACATAATGGTTTGT	gp1a	high	common
hsa-miR-15b-5p_R-3	19	TAGCAGCACATCATGGTTT	gp1a	high	common
hsa-miR-16-5p	22	TAGCAGCACGTAAATATTGGCG	gp1a	high	common
hsa-miR-17-5p	23	CAAAGTGCTTACAGTGCAGGTAG	gp1a	high	DGF specific
hsa-miR-181a-5p	23	AACATTCAACGCTGTCGGTGAGT	gp1a	middle	DGF specific
hsa-miR-185-5p	22	TGGAGAGAAAGGCAGTTCCTGA	gp1a	middle	DGF specific
hsa-miR-191-5p	23	CAACGGAATCCCAAAAGCAGCTG	gp1a	high	DGF specific
hsa-miR-199a-3p	22	ACAGTAGTCTGCACATTGGTTA	gp1a	middle	DGF specific
hsa-miR-19b-3p_R-2	21	TGTGCAAATCCATGCAAAACT	gp1a	middle	DGF specific
hsa-miR-20a-5p	23	TAAAGTGCTTATAGTGCAGGTAG	gp1a	high	DGF specific
hsa-miR-21-5p	22	TAGCTTATCAGACTGATGTTGA	gp1a	high	common
hsa-miR-221-3p_R-1	22	AGCTACATTGTCTGCTGGGTTT	gp1a	high	DGF specific
hsa-miR-223-3p_R+1	23	TGTCAGTTTGTCAAATACCCCAA	gp1a	high	DGF specific
hsa-miR-22-3p	22	AAGCTGCCAGTTGAAGAACTGT	gp1a	high	common
hsa-miR-22-5p_R-1	21	AGTTCTTCAGTGGCAAGCTTT	gp1a	middle	DGF specific
hsa-miR-23a-3p_R+1	22	ATCACATTGCCAGGGATTTCCA	gp1a	high	DGF specific
hsa-miR-23b-3p_R-5	18	ATCACATTGCCAGGGATT	gp1a	middle	DGF specific
hsa-miR-24-3p	22	TGGCTCAGTTCAGCAGGAACAG	gp1a	middle	DGF specific
hsa-miR-25-3p	22	CATTGCACTTGTCTCGGTCTGA	gp1a	high	common
hsa-miR-26a-5p	22	TTCAAGTAATCCAGGATAGGCT	gp1a	high	common
hsa-miR-26b-5p_R+1	22	TTCAAGTAATTCAGGATAGGTT	gp1a	high	common
hsa-miR-27a-3p_R-1	20	TTCACAGTGGCTAAGTTCCG	gp1a	high	common
hsa-miR-27b-3p	21	TTCACAGTGGCTAAGTTCTGC	gp1a	high	DGF specific
hsa-miR-29a-3p_R-1_1ss10CT	21	TAGCACCATTTGAAATCGGTT	gp1a	high	common
hsa-miR-29c-3p_R-1	21	TAGCACCATTTGAAATCGGTT	gp1a	high	common
hsa-miR-30a-5p_R+2	24	TGTAAACATCCTCGACTGGAAGCT	gp1a	high	DGF specific
hsa-miR-30b-5p	22	TGTAAACATCCTACACTCAGCT	gp1a	high	DGF specific
hsa-miR-30c-5p_R+1	24	TGTAAACATCCTACACTCTCAGCT	gp1a	high	DGF specific
hsa-miR-30d-5p_R+2	24	TGTAAACATCCCCGACTGGAAGCT	gp1a	high	DGF specific
hsa-miR-30e-5p_R+2	24	TGTAAACATCCTTGACTGGAAGCT	gp1a	high	DGF specific
hsa-miR-320a-3p	22	AAAAGCTGGGTTGAGAGGGCGA	gp1a	high	common
hsa-miR-339-5p_R-4	19	TCCCTGTCCTCCAGGAGCT	gp1a	middle	DGF specific
hsa-miR-33a-5p_R-1	20	GTGCATTGTAGTTGCATTGC	gp1a	middle	DGF specific
hsa-miR-363-3p_R-1	21	AATTGCACGGTATCCATCTGT	gp1a	middle	DGF specific
hsa-miR-378a-3p_R-1	21	ACTGGACTTGGAGTCAGAAGG	gp1a	high	DGF specific
hsa-miR-423-3p	23	AGCTCGGTCTGAGGCCCCTCAGT	gp1a	middle	DGF specific
hsa-miR-423-5p	23	TGAGGGGCAGAGAGCGAGACTTT	gp1a	middle	DGF specific
hsa-miR-425-5p_R-1	22	AATGACACGATCACTCCCGTTG	gp1a	middle	DGF specific
hsa-miR-451a_R-1	21	AAACCGTTACCATTACTGAGT	gp1a	high	common
hsa-miR-484_R-1	21	TCAGGCTCAGTCCCCTCCCGA	gp1a	middle	DGF specific
hsa-miR-486-5p	22	TCCTGTACTGAGCTGCCCCGAG	gp1a	high	common
hsa-miR-652-3p_R-1	20	AATGGCGCCACTAGGGTTGT	gp1a	middle	DGF specific
hsa-miR-92a-3p	22	TATTGCACTTGTCCCGGCCTGT	gp1a	high	common
hsa-miR-93-5p	23	CAAAGTGCTGTTCGTGCAGGTAG	gp1a	high	DGF specific
hsa-miR-98-5p	22	TGAGGTAGTAAGTTGTATTGTT	gp1a	middle	DGF specific
hsa-miR-99a-5p_R-1	21	AACCCGTAGATCCGATCTTGT	gp1a	high	DGF specific
hsa-miR-99b-5p	22	CACCCGTAGAACCGACCTTGCG	gp1a	middle	DGF specific
eca-miR-451_L+1R-1_1ss20TA	22	CAAACCGTTACCATTACTGAGT	gp2a	middle	DGF specific
efu-miR-9226_L-4_1ss22GA	18	GTCCCTGTTCGGGCGCCA	gp2a	middle	DGF specific
mmu-miR-3968_L-3_1ss14AT	18	ATCCCACTCCTGACACCA	gp2b	middle	DGF specific
cgr-miR-1260	18	ATCCCACCGCTGCCACCA	gp2b	middle	DGF specific
bta-miR-2478_L-2	18	ATCCCACTTCTGACACCA	gp3	middle	DGF specific
PC-3p-1061_715	18	AGTCCACGATCCCCGTGG	gp4	high	common
PC-3p-2112_237	19	CCCACCACGTTCCCCGTGG	gp4	middle	common
PC-3p-4600_77	19	TTCCACCACGTTCCCGGTG	gp4	middle	ctrl specific
PC-3p-4883_70	18	CACGTTCCCGGGCCGTGG	gp4	middle	common
PC-3p-857_1046	18	ATTCCAACGTTCCCGTGG	gp4	high	common
PC-5p-1596_363	18	GTTCCCGTGGTCCCGTGA	gp4	high	common
PC-5p-3627_109	18	CTCCACCACTTCCCGTGG	gp4	middle	common

gp1a: reads were mapped to miRNAs/pre-miRNAs of specific species in miRBase and the pre-miRNAs were further mapped to genome and EST. gp2a: reads were mapped to miRNAs/pre-miRNAs of selected species in miRBase and the mapped pre-miRNAs were not further mapped to genome, but the reads (and of course the miRNAs of the pre-miRNAs) were mapped to genome. The extended genome sequences from the genome loci may form hairpins. gp2b: reads were mapped to miRNAs/pre-miRNAs of selected species in miRBase and the mapped pre-miRNAs were not further mapped to genome, but the reads (and of course the miRNAs of the pre-miRNAs) were mapped to genome. The extended genome sequences from the genome loci may not form hairpins. gp3: reads were mapped to miRNAs/pre-miRNAs of selected species in miRBase and the mapped pre-miRNAs were not further mapped to genome, and the reads were not mapped to genome either. But the reads were mapped to the miRNAs (Matures). gp4: reads were not mapped to pre-miRNAs of selected species in miRBase. But the reads were mapped to genome and the extended genome sequences from genome may form hairpins.