AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway

<p><i>A schematic of the signalling pathways involved in AVE 0991-attenuated pyroptosis and hepatocyte damage induced by heat stress by inhibiting the ROS-NLRP3 inflammatory signalling pathway</i>. Ang II: angiotensin II; AT1R: angiotensin II type 1 receptor; ROS: reactive oxygen species; NOX: NADPH oxidase; NLRP3: NOD-like receptor family pyrin domain containing 3; IL-1<i>β</i>: interleukin-1<i>β</i>.</p>

BioMed Research International

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Figure 7

Figure 7: AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway 