BioMed Research International / 2019 / Article / Fig 7

Research Article

AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway

Figure 7

A schematic of the signalling pathways involved in AVE 0991-attenuated pyroptosis and hepatocyte damage induced by heat stress by inhibiting the ROS-NLRP3 inflammatory signalling pathway. Ang II: angiotensin II; AT1R: angiotensin II type 1 receptor; ROS: reactive oxygen species; NOX: NADPH oxidase; NLRP3: NOD-like receptor family pyrin domain containing 3; IL-1β: interleukin-1β.

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