Research Article

Prediction and Structural Comparison of Deleterious Coding Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Human LEP Gene Associated with Obesity

Table 2

Confirmation of the deleterious nsSNPs by other prediction software.

AA positionsPROVEAN_predPredictSNPMAPPPhD_SNPSNAPPANTHER

S46LDDDNDD
G59SDDDNDD
D61NDDDNDD
D100NDDDNDD
N103KDDDDDN
C117SDDDDDD
L161RDDDDDD
D76VDDDDDD
S88CDDDDDD
90RDDDDDD
I95NDDDDDD
R105WDDDDDD

D: Deleterious, N: Nondeleterious.