Research Article

Age- and Sex-Specific Reference Intervals for Myocardial Enzyme Activity in Healthy Chinese Han Population Aged 1∼<18 years

Table 4

Comparison of reference intervals for myocardial enzyme activity applied with similar detection systems and/or methodologies.

This studyOther country researchCao et al. [29]
System/methodAgeSexRISystem/methodAgeSexRISystem/methodAgeSexRI

AST (U/L)VITROS 5600/multipoint rate1∼<7M + F22.7–51.9VITROS 5600/rate [30]1∼<7M + F33–66VITROS 350/rate3 m∼<3 yM + F23–60
7∼<12M18.2–36.47∼<12M + F28–503 y∼<12 yM + F24–47
F16.0–33.812∼<18M24–4912∼<18M + F17–47
12∼<18M15.4–33.3F23–41
F13.7–26.6

LDH (U/L)VITROS 5600/multipoint rate1∼<7M + F434.9–737.7Abbott ARCHITECT/rate [30]1∼<10M + F309–1222VITROS 350/rate3 m∼<3 yM + F504–896
7∼<12M408.8–663.710∼<15M + F163–4523 y∼<12 yM + F491–790
F373.8–642.115∼<19M + F192–32112∼<18M + F342–716
12∼<15M364.8–641.0
15∼<18M314.6–568.6
12∼<18F315.7–554.9

CK (U/L)VITROS 5600/multipoint rate1∼<18M49.1–194.1VITROS/rate [31]13∼24 mM27–160VITROS 350/rate3 m∼<12 yM + F50–226
1∼<7F41.0–166.5F24–17512 y∼<18 yM47–256
7∼<12F39.3–155.42∼14M30–150F34–235
12∼<15F36.6–129.22∼10F24–175
15∼<18F32.0–105.911∼14F30–170
15∼18M33–145
F27–140

CKMB (U/L)VITROS 5600/multipoint rate1∼<7M + F11.4–38.9VITROS 350/rate3 m∼<6 yM + F18–44
7∼<15M7.9–34.26 y∼<12 yM + F7–35
7∼<12F7.4–30.712 y∼<18 yM + F7–28
12∼<15F2.8–23.3
15∼<18F2.7–15.5
15∼<18M2.1–20.8

Lowest detection limit. Actual values could be lower.