Cigarette Smoke Induced Lung Barrier Dysfunction, EMT, and Tissue Remodeling: A Possible Link between COPD and Lung Cancer

Table 1

Comparison of epithelial endothelial and mesenchymal cells.

	Epithelial cell	Endothelial cell	Mesenchymal cell
junctions	AJs, TJs,; Desmosomes; w/E-cadherin	AJs, limited TJs,; W/VE-cadherin	-
Barrier function	++	+	-
Intermediate filament	Cytokeratin	Vimentin	Vimentin
Markers	Claudins; Occludins; Cytokeratin; Mucin-1; E-cadherin	CD31; VE-cadherin; VEGFR; Tie	α-SMA; vimentin; FSP1; Vitronectin