Research Article

Improvement of Disease Management and Cost Effectiveness in Chinese Patients with Ankylosing Spondylitis Using a Smart-Phone Management System: A Prospective Cohort Study

Table 3

Characteristics of disease activity at baseline and a mean (SD) follow-up of 13.3 (5.9) months.

CharacteristicsID/LDA at baseline 
(n=445, 57.2%)
Active at baseline 
(n=332, 42.7%)
Maintainer of ID/LDA (n=410, 92.1%)Patients with relapse (n=35, 7.9%)P valueMaintainer of active disease (n=127, 38.2%)New achiever of ID/LDA (n=205, 61.7%)P value

Age, mean (S.D.), years30.2 (9.1)29.8 (7.6)0.78530.8 (8.6)30.6 (8.3)0.816
Disease duration, mean (S.D.), years7.6 (6.2)7.3 (5.6)0.7879.0(6.1)9.3(6.1)0.714
Number of self-assessments, mean (S.D.)5.0 (2.7)3.3 (1.8)<0.0014.5(2.5)5.6(3.1)<0.001
Male sex, %79.888.60.20789.883.90.133
ASDAS at baseline, mean (S.D.)1.4 (0.5)1.5 (0.4)0.0313.2 (0.8)3.0 (0.8)0.134
Smoker, %24.740.00.04744.032.80.042
NSAIDs at baseline, %98.199.80.44897.999.40.263
TNFi at baseline, %19.213.80.47924.529.80.359
csDMARDs at baseline, %64.072.40.36366.068.50.679
TNFi during the follow-up perio, %29.927.30.75532.345.60.016

TNFi during the follow-up period: used TNFi at any point beginning from the time of enrolment in the registry (the first visit) and during the follow-up visits. ID: inactive disease, LDA: low disease activity, ASDAS: Ankylosing Spondylitis Disease Activity Score; NSAIDs: non-steroidal anti-inflammatory drugs; TNFi: TNF inhibitors; csDMARDs: conventional synthetic disease modifying anti-rheumatic drug; P < 0.05.