Research Article
Clinical and Laboratory Characteristics of Symptomatic and Asymptomatic Neurosyphilis in HIV-Negative Patients: A Retrospective Study of 264 Cases
Table 2
Univariate and multivariate analysis for clinical and laboratory predictors of SNS patients.
| | Factors | Univariate | Multivariate | | ā | OR (95%CI) | P-value | OR (95%CI) | P-value |
| | Sex, male vs female | 4.556 (2.591~8.010) | P<0.001 | 2.833 (1.394~5.880) | P=0.009 | | Age, ā„45 vs < 45, years | 3.928 (2.308~6.684) | P<0.001 | 3.611 (1.713~7.612) | P=0.001 | | Treatment history, no vs yes | 0.357 (0.215~0.591) | P<0.001 | 0.247 (0.119~0.512) | P<0.001 | | Pretreatment serum RPR titer | 1.246 (1.060~1.464) | P=0.008 | 0.837 (0.643~1.090) | P=0.187 | | Current RPR titer | 1.579 (1.337~1.865) | P<0.001 | 1.373 (1.047~1.800) | P=0.022 | | Serum FTA-ABS-IgM, + vs - | 1.734 (0.994~3.026) | P=0.053 | 0.957 (0.413~2.215) | P=0.917 | | CSF protein concentration, mg/dl | 1.032 (1.020~1.046) | P<0.001 | 1.017 (1.002~1.033) | P=0.026 | | CSF WBC count, /ul | 1.012 (1.004~1.021) | P=0.005 | 1.001 (0.992~1.010) | P=0.816 | | CSF RPP, + vs - | 9.208 (5.215~16.258) | P<0.001 | 4.616 (2.185~9.752) | P<0.001 |
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Abbreviation: ANS=asymptomatic neurosyphilis; SNS=symptomatic neurosyphilis; RPR = rapid plasma regain; TPPA=Treponema pallidum particle agglutination; CSF=cerebrospinal fluid; WBC=white blood cells; FTA-ABS=fluorescent treponemal antibody absorption; OR=odds ratio; CI=confidence interval;
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