Research Article
Identification of Potential Transcriptional Biomarkers Differently Expressed in Both S. aureus- and E. coli-Induced Sepsis via Integrated Analysis
Table 3
Enriched pathways for the upregulation genes in Staphylococcus aureus and Escherichia coli samples.
(a) Staphylococcus aureus |
| | KEGG Term | Function description | Gene count | P-value | Gene symbol |
| | ptr04668 | TNF signaling pathway | 3 | 1.17E-02 | IL18R1, SOCS3, MMP9 | | ptr00051 | Fructose and mannose metabolism | 2 | 4.93E-02 | PFKFB3, HK3 |
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(b) Escherichia coli |
| | KEGG Term | Function description | Gene count | P-value | Gene symbol |
| | ptr00051 | Fructose and mannose metabolism | 3 | 4.05E-03 | PFKFB3, HK3, PFKFB2 | | ptr05321 | Inflammatory bowel disease (IBD) | 3 | 1.65E-02 | IL18R1, IL18RAP, TLR5 | | ptr04668 | TNF signaling pathway | 3 | 4.05E-02 | IL18R1, SOCS3, MMP9 |
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Note. KEGG: Kyoto Encyclopedia of Genes and Genomes; TNF: tumor necrosis factor.
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