Identification of CTRP1 as a Prognostic Biomarker and Oncogene in Human Glioblastoma
Figure 1
Overexpression of CTRP1 mRNAs and its protein location in GBM patients. (a) The box plot image showed mRNA levels of CTRP1 in GBM tissues (T) (N=163) and nontumor tissues (N) (N=207) from GEPIA (http://gepia.cancer-pku.cn/index.html). The datasets (“TCGA tumors vs TCGA normal + GTEx normal”) were selected for the differential analysis. According to the instructions of GEPIA, one-way ANOVA was used for the differential analysis, and the disease state (Tumor or Normal) was used as a variable for calculating differential expression. A P < 0.05 was considered statistically significant. (b) The immunohistochemical image of CTRP1 in Glioblastoma tissue from the Pathology Atlas of the Human Protein Atlas (https://www.proteinatlas.org/pathology). The patient ID was 1642. The scale bars were 25 um. (c) The expression of CTRP1 in glioblastoma and brain normal tissues was detected by immunohistochemistry. Photomicrographs were taken at 100x and 400x magnification, respectively. P < 0.05.