Moringa peregrina Leaves Extracts Induce Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma

Figure 4

Moringa leaves extracts induce cell cycle arrest and apoptosis in HepG2 cells. Cells treated for 48 hours with 4 Moringa leaves extracts including (a) P/DEE, (b) P/EA, (c) O/DEE, (d) O/EA, and (e) untreated cells as controls. The cell cycle distribution was determined by propidium iodide staining (PI) and flow cytometry. Left panels show the distribution and the percentage of cells in phases of the cell cycle. Right panels show the distribution and the percentage of cells of apoptotic cells (Annexin⁺). The cell cycle phases G1, S, and G2/M are indicated over the peaks. PI: cell survival marker; Annexin V: apoptotic marker.

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