Research Article
Identification of a Novel NF1 Frameshift Variant in a Chinese Family with Neurofibromatosis Type 1
Figure 4
Apoptosis and western blotting measures. The apoptosis (a) and western blotting (b) were analyzed in HEK293T cells overexpressed control or NF1 p.(Gln181Profs20) variant or NF1 WT. All data from 3 independent experiments were represented as the mean ± standard deviation (two-way ANOVA, , , and ). The results revealed the p.(Gln181Profs20) variant partly abolished NF1-induced apoptosis.
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