Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors

Table 1

Univariate analysis of factors that modify significantly the retinal vascular development: intubation days (d), BPD 3, weight gain at 4-6 weeks (gr/days), avascular temporal area (DD), gestational age (weeks), sepsis, apnea at birth, ductus arteriosus, and CPAP therapy (days).

Risk factor	Odds ratio (CI 95%)	P-value R^2	Nagelkerke
Intubation days (d)	1.068 (1.03-1.10)	<0.01	15.9%
BPD 3	1.57 (1.2-2.07)	0.01	8.6%
Weight gain (gr/day)	0.92 (0.86-0.97)	0.04	6.9%
Avascular temporal area	1.325 (1.1-1.59)	0.003	6.7%
Gestational age	0.79 (0.68-0.93)	0.04	6.2%
Transfusions number	1.80 (1.12-2.89)	0.015	4.9%
Sepsis	2.21 (1.19-4.1)	0.012	4.7%
Number of risk factors	1.14 (1.02-1.27)	0.024	3.9%
Apnea at birth	2.54 (1.12-5.75)	0.025	3.7%
Ductus arteriosus	2.36 (1.08-5.15)	0.032	3.4%
Days of CPAP therapy	1.05 (1.003-1.10)	0.039	3.2%