In Silico Integration Approach Reveals Key MicroRNAs and Their Target Genes in Follicular Thyroid Carcinoma

Table 2

Gene ontology analysis of intersection genes.

Category	Term	Count	P value	Benjamini	Genes
GOTERM_BP_DIRECT	GO: 0014066~regulation of phosphatidylinositol 3-kinase signaling	3	0.001364	0.128529	EGFR, KIT, IRS1
GOTERM_BP_DIRECT	GO: 0046854~phosphatidylinositol phosphorylation	3	0.001973	0.085255	EGFR, KIT, IRS1
GOTERM_BP_DIRECT	GO: 0048015~phosphatidylinositol-mediated signaling	3	0.0025	0.066478	EGFR, KIT, IRS1
GOTERM_BP_DIRECT	GO: 0008284~positive regulation of cell proliferation	4	0.003875	0.041446	EGFR, CCND2, KIT, IRS1
GOTERM_BP_DIRECT	GO: 0010628~positive regulation of gene expression	3	0.014438	0.29193	CDK6, KIT, KLF4
GOTERM_CC_DIRECT	GO: 0000307~cyclin-dependent protein kinase holoenzyme complex	2	0.011466	0.285394	CCND2, CDK6
GOTERM_MF_DIRECT	GO: 0046934~phosphatidylinositol-4,5-bisphosphate 3-kinase activity	3	8.55E-04	0.028534	EGFR, KIT, IRS1
GOTERM_MF_DIRECT	GO: 0005088~Ras guanyl-nucleotide exchange factor activity	3	0.002904	0.048361	EGFR, KIT, IRS1
GOTERM_MF_DIRECT	GO: 0004716~receptor signaling protein tyrosine kinase activity	2	0.007088	0.117378	EGFR, KIT
GOTERM_MF_DIRECT	GO: 0004714~transmembrane receptor protein tyrosine kinase activity	2	0.026689	0.299626	EGFR, KIT