Research Article

MiR-21-3p Plays a Crucial Role in Metabolism Alteration of Renal Tubular Epithelial Cells during Sepsis Associated Acute Kidney Injury via AKT/CDK2-FOXO1 Pathway

Figure 2

Alterations of metabolism and FOXO1 expression in TECs during SAKI. (a) Representative images of Oil Red O staining of kidney sections from different rat groups at each time point. (b) Quantitative analysis of Oil Red O staining (: P<0.05 vs. Control; #: P<0.05 vs. CLP group at the same time point). (c) Quantitative analysis of ADT/ATP Ratio of TECs from different rat groups at each time point (: P<0.05 vs. Control; #: P<0.05 vs. CLP group at the same time point). (d) Representative Western-Blotting results of FOXO1 of TECs from Ctrl and CLP groups at 12 h after the surgery (: P<0.05 vs. Control).

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