Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats

Table 1

Effect of Adansonia digitales leaves extract on body weight (gm) of diabetic rats.

Treatment		Time in week
		0	2	4	6
Normal control		183.00±3.11	234.13±7.47	269.56±11.43	280.00±7.00
Diabetic control		193.42±8..63	190.00±5.48	181.00±8.21	172.00±9.00
Diabetic + GBC (5mg/Kg)		177.00±6.10	230.66±4.92	254.00±7.00	266.03±8.43
Diabetic + Leaf extract	200mg/Kg	200.23±5.79	210.00.±3.79	230.14±8.00	236.87±10.00
	400mg/Kg	190.76±7.14	240.89±6.84	255.76±11.05	250.88±8.69

All the data has been expressed as mean ± SEM of eight independent samples from each group () analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.