Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats

Table 2

Effect of Adansonia digitales leaves extract on blood cholesterol level (mg/dl) of diabetic rats.

Treatment		Time in week
		0	2	4	6
Normal control		70.32±1.75	74.65±4.27	82.56±4.93	75.69±4.83
Diabetic control		161.86±3.99	168.40±8.11	177.61±5.65	180.36 ±7.44
Diabetic +GBC (5 mg/Kg)		170.38±5.00	140.17±7.66	115.45±3.22	77.15±3.85
Diabetic + Leaf extract	200 mg/Kg	176.91±9.22	169.20±5.88@	154.03±4.64@	142.19±5.23@
	400 mg/Kg	189.00 ± 8.02	150.22±3.28	133.45±6.57	91.78±5.61

All the data has been expressed as mean ± SEM of eight independent samples from each group () analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.