Research Article

Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats

Table 4

Effect Adansonia digitales leaf extract on blood HDL (mg/dl) of diabetic rats.

TreatmentTime in week
0246

Normal control35.54±1.3540.58±2.1936.14±1.2638.91±2.17
Diabetic control41.71 ±1.6738.32 ±0.3430.00±0.9729.12 ±0.86
Diabetic +GBC (5 mg/Kg)37.65±1.4638.16±2.5441.66±2.0342.15±3.96
Diabetic + Leaf extract200 mg/Kg45.22 ±2.6644.15±2.4136.11 ±0.8931.34±1.50
400 mg/Kg40.37 ±1.6745.61 ±1.0937. 06 ±1.6338.85±2.17

All the data has been expressed as mean ± SEM of eight independent samples from each group (8) analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.