Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats

Table 5

Effect of Adansonia digitales leaves extract on blood LDL (mg/dl) in diabetic rats.

Treatment		Time in week
		0	2	4	6
Normal control		19.73±0.54	22.05±1.13	20.48±1.05	18.86±0.73
Diabetic control		110.00±1.91	100.25±3.44	96.14 ±2.00	98.45 ±3.85
Diabetic + GBC (5 mg/Kg)		97.80±5.26	66.48±3.15	41.96±2.69	33.07±1.72
Diabetic +Leaf extract	200 mg/Kg	100.88±2.05	93.22 ±3.03@	80.32±2.11@	61.30±4.01@
	400 mg/Kg	102.48 ±3.97	77.32 ±1.74@	51.86±2.08@	39.65. ±1.07

All the data has been expressed as mean ± SEM of eight independent samples from each group () analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.