Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats

Table 6

Effect of Adansonia digitales leaf extract on blood cell count, glycosylated hemoglobin, and erythropoietin of diabetic rats.

Parameters	Groups
	Normal control	Diabetic control	Diabetic + Leaf extract		Diabetic + GBC 0.5 mg/Kg
			200 mg/kg	400 mg/kg
RBCs count (x10^6/ml)	7.50±0.46	4.00 ±0.25	4.70±0.11@	5.33±0.25@	6.11 ±0.16
WBCs count (x10^5/ml)	5.40 ±0.23	12.50±0.65	9.76±0.47@	8.00±0.41	7.65±0.58
Hb level (g/dl)	16.00±1.04	11.85±0.49	12.50±0.23@	14.78±0.54	14.90±0.36
PCV (%)	50.00±2.96	35.19±1.28	44.00±2.18@	53.39±3.21	54.00±3.25
GHb (%)	4.56±0.07	13.00±0.48	8.60 ±0.54@	7.00±0.16	7.50±0.68
EPO (ng/ml)	2.78±0.04	0.58±0.01	1.34±0.05@	1.86±0.03@	2.20±0.06

All the data has been expressed as mean ± SEM of eight independent samples from each group () analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.
GBC: glibenclamide; GHb: glycosylated hemoglobin; EPO: Erythropoietin.