Research Article

Glycopatterns and Glycoproteins Changes in MCN and SCN: A Prospective Cohort Study

Figure 5

Glycoproteins by differential lectin binding in MCN and SCN. (a) Four-way Venn diagram: WGA- MCN, WGA-SCN, STL-MCN, and STL-SCN in a cross-statistic chart. (b) The Heat map of WGA-binding glycoproteins in MCN and SCN. The samples were listed in columns, and the proteins were listed in rows. The colour and intensity of each square indicated expression levels relative to the other data in the row. Red, high; green, low; black, medium. (c) The Heat map of STL-binding glycoproteins in MCN and SCN. The colour and intensity of each square indicated expression levels relative to the other data in the row. Red, high; green, low; black, medium. (d) String network interaction of APOA1, VTN, C5, and S100A9 genes significantly enriched in WGA-binding glycoproteomics. (e) String network interaction of APOE, ECM1, MUC5B, CP, KLKB1, and PLG genes significantly enriched in STL-binding glycoproteomics.

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