Glycopatterns and Glycoproteins Changes in MCN and SCN: A Prospective Cohort Study

Table 4

The protein enrichment by STL in MCN versus SCN.

Protein name	Gene name	Majority protein IDs	Normalized relative intensity		MCN/SCN; Ratio
			MCN	SCN
(A) Increased expression
Ig lambda-7 chain C region	IGLL1	A0M8Q6	12.35 ± 10.23	1.38 ± 0.08	8.95
Haptoglobin	HP	P00738	15.42 ± 1.67	10.13 ± 0.88	1.52
Plasminogen	PLG	P00747	14.19 ± 1.29	10.48 ± 0.50	1.35
Apolipoprotein A-I	APOA1	P02647	195.25 ± 8.29	160.44 ± 14.22	1.22
Apolipoprotein E	APOE	P02649	48.10 ± 2.26	34.68 ± 0.53	1.39
Fibrinogen Alpha A	FGA	P02671	44.56 ± 3.31	29.25 ± 1.01	1.52
Fibrinogen gamma chain	FGG	P02679	35.71 ± 4.92	21.61 ± 1.32	1.65
Clusterin	CLU	P10909	8.70 ± 1.07	5.36 ± 0.50	1.62
Inter-alpha-trypsin inhibitor heavy chain H2	ITIH2	P19823	10.27 ± 0.70	6.62 ± 0.96	1.55
Actin, gamma 1	ACTG1	P63261	4.21 ± 0.32	2.34 ± 0.18	1.8
(B) Decreased expression
Alpha-2-macroglobulin	A2M	P01023	13.27 ± 0.43	35.82 ± 4.42	0.37
Ig alpha-1 chain C region	IGHA1	P01876	18.50 ± 1.83	29.41 ± 0.56	0.63
Apolipoprotein A-II	APOA2	P02652	39.36 ± 7.77	62.11 ± 7.96	0.63
Apolipoprotein A-IV	APOA4	P06727	2.45 ± 0.09	5.36 ± 1.04	0.46
Complement component C8 alpha chain	C8A	P07357	2.17 ± 0.12	2.73 ± 0.16	0.8
Hemoglobin subunit beta	HBB	P68871	97.91 ± 6.10	308.30 ± 10.39	0.32