Association between Retinal Nerve Fiber Layer Thickness and Eye Fatigue

Table 1

Comparison of parameters between groups with and without eye fatigue.

Parameters	Eye fatigue (-)	Eye fatigue (+)	P value
No. of subjects	254	123
Age (years)	58.4 ± 18.1	54.4 ± 15.8	0.013
% of men	55.9	48.8	0.196
Symptomatology
Blurring (%)	15.0	28.5	0.004
Photophobia (%)	11.1	24.4	0.003
Pain (%)	2.4	8.9	0.018
Irritation (%)	8.7	23.6	0.001
Dryness (%)	11.4	33.3	< 0.001
Ocular surface parameters
Schirmer test (% ≤ 5 mm)	21.7	13.3	0.511
Maximum blinking interval (% ≤ 9 s)	4.3	18.9	< 0.001
Refractive and accommodative parameters
Spherical error (diopter)	–2.00 ± 3.14	–2.48 ± 3.36	0.209
Cylindrical error (diopter)	0.78 ± 0.71	0.84 ± 0.68	0.279
Spherical equivalent (diopter)	–2.39 ± 3.13	–2.84 ± 3.41	0.254
Anisometropia (diopter)	0.64 ± 0.77	0.65 ± 0.72	0.855
Near add power (diopter)	1.42 ± 0.18	1.49 ± 0.16	0.620
Retinal thickness
Macular ganglion cell complex (μm), mean	100.3 ± 13.4	103.8 ± 14.1	0.014
Superior right (μm)	99.2 ± 15.4	103.0 ± 15.1	0.128
Superior left (μm)	99.2 ± 16.2	103.4 ± 16.7	0.008
Inferior right (μm)	101.4 ± 18.2	105.2 ± 18.6	0.033
Inferior left (μm)	101.2 ± 18.1	105.3 ± 18.3	0.021
Full retinal thickness of whole macula (μm)	266.1 ± 24.3	265.9 ± 26.1	0.976

P < 0.05, Chi squared test and t-test as appropriate.