Effects of Twin Inclined Plane Device on Adaptation and Ultrastructure Variations in Condyle of Growing Rats

Figure 5

Analysis of the expression of VEGF, Type II collagen, and osteoclasts in the posterior condylar area. (a) The VEGF expression in the posterior part of the condyle in the control group and experimental group. The significant difference was annotated on days 30 and 60 between the experimental and control groups (, ). (b) The expression of type II collagen decreased in the posterior part of the condyle within 30–60 days in the control and experimental groups. A significant difference was annotated on days 30 and 60 (, ). (c) The thickness of the mature and hypertrophic layer presented by type II collagen in the posterior part of the condyle in the control and experimental groups. A significant difference in thickness was observed in the control and experimental groups at day 30 and 60 (, ). (d) TRAP-positive cells were observed under the subchondral bone in the control and experimental groups. Significant differences in the number of osteoclasts in animals in the experimental and control groups were observed at day 30 and day 60 (, , ).

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