Research Article
α-1-Acid Glycoprotein Concentration as an Outcome Predictor in Adult Patients with Sepsis
Table 3
Comparisons of clinical features between sepsis and septic shock patients.
| | | Sepsis | Septic shock | p value | | n = 16 | n = 71 |
| | Age (y) (mean ± SD) | 63.8 ± 16.0 | 65.5 ± 14.8 | 0.69 | | Male/Female (n) | 13/3 | 46/25 | 0.20 | | Potential diseases [n (%)] | | | | | Diabetes | 4 (25.0) | 24 (33.8) | 0.50 | | Hypertension | 8 (52.0 | 37 (52.1) | 0.88 | | Chronic lung disease | 2 (12.5) | 7 (9.9) | 0.75 | | Cerebrovascular disease | 3 (18.8) | 9 (12.7) | 0.52 | | Chronic heart disease | 2 (12.5) | 3 (4.2) | 0.20 | | Chronic renal disease | 3 (18.8) | 19 (26.8) | 0.51 | | Clinical presentations (mean ± SD) | | | | | Systolic BP (mmHg) | 140.1 ± 31.1 | 85.6 ± 25.7 | P<0.01 | | Heart rate (bpm) | 113.7 ± 28.7 | 109.4 ± 25.5 | 0.56 | | Clinical severity index (mean ± SD) | | | | | Maximum 24-h APACHE II score | 17.8 ± 5.3 | 20.6 ± 7.8 | 0.17 | | Bacteremia [n (%)] | 5 (31.3) | 28 (39.4) | 0.54 | | Intervention within 24 hours [n (%)] | | | | | Mechanical ventilator | 5 (31.3) | 25 (35.2) | 0.76 | | Vasoactive agent | 0 (0) | 6 (8.5) | 0.37 | | Expired [n (%)] | 1 (6.3) | 18 | 0.10 | | Laboratory data (mean ± SD) | | | | | White blood cells (×109/L) | 12.0 ± 6.7 | 15.0 ± 8.0 | 0.18 | | Hemoglobin (mg/dL) | 11.4 ± 1.5 | 12.0 ± 2.3 | 0.32 | | Platelet counts (×104/L) | 205.2 ± 122.8 | 171.3 ± 100.0 | 0.24 | | C-reactive protein (mg/L) | 113.9 ± 86.7 | 182.0 ± 109.0 | 0.02 | | Lactate (mg/dL) | 27.0 ± 10.8 | 32.6 ± 11.9 | 0.10 | | Cr (mg/dL) | 2.1 ± 2.6 | 2.7 ± 2.5 | 0.41 | | Procacitonin (ng/mL) | 9.1 ± 8.9. | 28.0 ± 18.6 | 0.67 | | AGP (ng/ml) | 1080.1 ± 354.0 | 1150.9 ± 408.3 | 0.52 |
|
|
SD, standard deviation; APACHE, Acute Physiology and Chronic Health Evaluation
|
