Reevaluating the Role of Corticosteroids in Septic Shock: An Updated Meta-Analysis of Randomized Controlled Trials

Figure 5

Results of trial sequential analysis for 28-day all-cause mortality. A diversity-adjusted information size of 10044 patients was calculated based on an anticipated RRR of 7% (event proportion of 40% in the control arm, α=0.05 [two-sided]; β=0.20 [power 80%]).