Research Article
Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity
Table 2
Cardiovascular parameters in 70 patients with RA and without CVD.
| | Characteristics | Overall
(n=70) | Female
(n=54) | Male
(n=16) | p
(F vs. M) |
| | Traditional CVD risk factors | | SBP, mmHg | 128.3 (9.4) | 128.1 (9.9) | 128.8 (7.4) | 0.8 | | DBP, mmHg | 81.0 (7.4) | 80.5 (7.8) | 82.8 (5.5) | 0.3 | | Serum glucose, mg/dl | 91.9 (5.2) | 92.0 (5.3) | 91.5 (4.9) | 0.7 | | BMI, kg/m2 | 25.5 (3.2) | 25.2 (4.1) | 25.5 (3.2) | 0.8 | | Total cholesterol, mg/dl | 196.7 (38.9) | 195.6 (35.7) | 200.6 (49.6) | 0.7 | | HDL cholesterol, mg/dl | 57.0 (14.5) | 59.0 (14.6) | 50.2 (12.0) | 0.03 | | LDL cholesterol, mg/dl | 116.8 (35.7) | 114.6 (32.9) | 124.0 (44.1) | 0.4 | | Triglycerides, mg/dl | 113.6 (55.4) | 109.3 (39.9) | 128.1 (90.4) | 0.2 | | Atherogenic index | 3.6 (1.2) | 3.4 (1.0) | 4.2 (1.4) | 0.03 | | Non-smoker | 63 (90.0) | 52 (96.3) | 11 (68.8) | 0.001 | | Current/ Ex-smoker | 7 (10.0) | 2 (3.7) | 5 (31.2) | 0.001 | | mSCORE, % | 3.43 (3.19) | 2.76 (2.73) | 5.69 (3.68) | <0.001 | | High/Very high risk of CV death | 23 (32.9) | 13 (24.1) | 10 (62.5) | 0.004 | | Ultrasonography of carotid arteries | | cIMT, mm | 0.83 (0.21) | 0.80 (0.2) | 0.93 (0.2) | 0.04 | | Normal cIMT (<0.6 mm) | 10 (14.3) | 10 (18.5) | 0 | 0.6 | | cIMT ≥ 0.6 and <0.9 mm | 34 (48.6) | 26 (48.2) | 8 (50.0) | 0.9 | | Arterial wall hypertrophy >0.9 mm | 26 (37.1) | 18 (33.3) | 8 (50.0) | 0.2 | | Echocardiography | | E/A ratio | 1.08 (0.28) | 1.1 (0.28) | 1.03 (0.29) | 0.4 | | EF, % | 59.8 (1.6) | 60 (0.97) | 59.1 (2.72) | 0.5 | | Electrocardiogram: QTc, ms | 439.6 (23.7) | 441.2 (22.9) | 433.9 (26.0) | 0.3 | | NT-proBNP, pg/ml | 97.6 (63.4) | 106.8 (61.5) | 66.6 (61.2) | 0.02 |
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Values are presented as mean (SD) (range) or number (%).
Abbreviations: BMI, body mass index; cIMT, carotid intima media thickness; CVD, cardiovascular disease; DBP, diastolic blood pressure; EF, ejection fraction; HDL cholesterol, high-density lipoprotein cholesterol; LDL cholesterol, low-density lipoprotein cholesterol; mSCORE, multiplied systemic coronary risk evaluation; NT-proBNP, amino-terminal pro-brain natriuretic peptide; SBP, systolic blood pressure.
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