Bioactivities of Flavonoids from Lopezia racemosa

Table 1

Antimicrobial activities of L. racemosa extracts against a panel of bacteria and fungi expressed in MIC (μg/mL).

Fraction

Bacteria

Fungi

AB

BS

EC

MRSA

PA

SA

SAL

SE

AF

CA

CN

TM

Leaves

377-382

R

R

R

R

R

R

R

500

R

R

R

R

383-396

R

R

R

R

R

R

R

500

R

R

R

R

414-417

R

R

R

R

R

R

R

R

R

R

R

250

447-506

R

R

R

R

R

R

R

R

R

R

R

125

507-516

R

R

R

R

500

R

R

R

R

R

R

R

524-525

R

R

R

R

R

R

R

500

R

R

R

250

528-533

R

R

R

R

500

R

R

500

R

R

R

R

542-547

R

R

R

R

R

R

500

R

R

R

R

R

594-603

R

R

R

R

R

R

R

R

R

R

R

500

744-749

R

R

R

500

250

500

R

R

R

R

R

R

775-784

R

R

R

R

500

500

R

R

R

R

R

R

785-794

R

R

R

R

500

R

R

R

R

R

R

500

799-810

R

R

R

R

R

R

R

R

R

R

R

500

821-833

R

R

R

R

500

R

R

R

R

R

R

R

834-844

R

R

R

R

250

R

R

R

R

R

R

R

845-851

R

R

R

R

250

R

R

R

500

R

R

R

852-856

R

R

R

500

50

500

250

500

R

R

R

R

925-941

R

R

R

R

250

R

R

R

R

R

R

R

Flowers

171-180

250

500

R

R

500

R

R

R

R

R

R

R

181-190

R

R

R

R

R

R

R

500

R

R

R

R

255-262

R

R

R

R

500

R

R

R

R

R

R

R

304-310

R

R

R

R

100

R

R

R

R

R

R

R

Control

0.1

15

10

10

60

0.7

10

1

2

2

2

1

AB, Acinetobacter baumannii; BS, Bacillus subtilis; EC, Escherichia coli; EF, Enterococcus faecalis; MRSA, methicillin-resistant Staphylococcus aureus; MS, Mycobacterium smegmatis; PA, Pseudomonas aeruginosa; SA, Staphylococcus aureus; AF, Aspergillus fumigatus; CA, Candida albicans; CN, Cryptococcus neoformans; TR, Trichophyton mentagrophytes. R, resistant. Amikacin, Gentamicin, Rifampicin, Amphotericin B, Terbinafine. Experiments were performed in triplicate.