|Model system||Intervention||Dose and duration||Results||Conclusions||Ref.|
|Diet-induced obesity mice model||Lactobacillus rhamnosus PB01 (DSM 14870)||1 × 109 CFU per day for 4 weeks||↑ Serum testosterone, FSH and LH levels.|
↑ Sperm kinetics
↑ Highly active motile sperm level.
↓ Non-motile sperm count.
|DSM 14870 supplementation increased sperm kinetics and amount of active motile sperm in diet-induced obese mice.|||
|Diet-induced obesity mice model||L. rhamnosus and ultrasound||1 × 108 CFU per|
day for 8 weeks
|↓ Body weight, total body fat.|
↓ Thickness of the subcutaneous fat layer.
Improved the plasma lipid profile.
|L. rhamnosus supplementation with ultrasound treatment effectively reduced the fat content and improved lipid profile in diet-induced obese mice.|||
|High-energy-diet-fed rats||L. reuteri 263||2.1 × 109 CFU per kg per day for 8 weeks or 1.05 ×1010 CFU per kg per day for 8 weeks||↑ Proinflammatory factors and antioxidant enzymes.|
↑ Oxygen consumption.
↑ Expression of genes associated with thermogenesis, glucose and lipid metabolism.
|L. reuteri 263 supplementation improved the obese condition via remodeling of energy metabolism in the high-energy-diet fed rat model.|||
|High-fat diet rat||L. plantarum and L. fermentum||1 × 108 CFU per day for 8 weeks||↓ Fat vehicle sizes, liver steatosis, endotoxin, IL-6 level|
↑ Lactobacillus and Bifidobacterium content.
|Probiotic supplementation altered the microbiota and inflammatory system in the high-fat-diet fed rat model.|||
|High-fat-diet-induced obese mice||Soy-based probiotic drink|
(B. longum ATCC15707 and Enterococcus faecium CRL183)
|1 × 108 CFU per day for 70 days||↓ IL-6, IL-10.|
↓ Size of adipocytes, Body weight gain.
↑ Bifidobacterium and Lactobacillus content.
|Probiotic soy drink positively regulated the intestinal microbiota and immune profile of the high-fat-diet induced obese mice model.|||
|High-fat-diet induced obese rat||Probiotic formula|
(L. rhamnosus LR5, L. acidophilus LA1, S. thermophilus ST3, B. longum BG7, B. lactis BL3, and B. bifidum BF3)
|1 × 107 CFU per day for 8 weeks||↓ Body weight|
↑ Lactobacillus, Bacteroidetes, and
Improved the serum level metabolic profile.
|Probiotic supplementation diminished the consequences of high-fat-diet induced obesity in the high-fat-diet induced obese rat model.|||