Genetic Variants in Group-Specific Component (GC) Gene Are Associated with Breast Cancer Risk among Chinese Women

Table 5

Combined effects on breast cancer risk.

Number of protective alleles^b	Cases	Controls	OR (95% CI)^a
	N (%)	N (%)
0	363 (46.30)	390 (43.29)	1.00
1–2	11 (1.40)	12 (1.33)	0.90 (0.37–2.20)	0.816
3–6	410 (52.30)	499 (55.38)	0.81 (0.66–0.99)	0.044
for trend				0.043

^aAdjusted by age, menopausal status, BMI, family history, income, waist circumference, and education. ^bCombined genotypes were according to protective alleles carried (rs17467825-G, rs2298850-C, and rs3755967-T).