Research Article
Atopic Eczema: Genetic Analysis of COL6A5, COL8A1, and COL10A1 in Mediterranean Populations
Table 2
Biostatistical results obtained by analysis on Greek case and control subjects.
| Gene (SNP) | Population (N) | Genotypes (Frequency) | Alleles (Frequency) | P | OR (95%CI) |
| COL6A5 (rs12488457, A/C) | Greek (56) | AA: 6 (0.11) AC: 24 (0.43) CC: 26 (0.46) | A: 36 (0.32) C: 76 (0.68) | ns | - | Greek Controls (50) | AA: 8 (0.16) AC: 18 (0.36) CC: 24 (0.48) | A: 34 (0.34) C: 66 (0.66) |
| COL8A1 (rs13081855, G/T) | Greek (56) | GG: 51 (0.91) GT: 5 (0.09) TT: 0 (0.00) | G: 107 (0.96) T: 5 (0.04) | ns | - | Greek Controls (50) | GG: 40 (0.80) GT: 10 (0.20) TT: 0 (0.00) | G: 90 (0.90) T: 10 (0.10) |
| COL10A1 (rs3812111, A/T) | Greek (56) | AA: 2 (0.04) AT: 23 (0.41) TT: 31 (0.55) | A: 27 (0.24) T: 85 (0.76) | ns | - | Greek Controls (48) | AA: 6 (0.125) AT: 18 (0.375) TT: 24 (0.500) | A: 30 (0.31) T: 66 (0.69) |
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