Different Methylation of CpG-SNPs in Behcet’s Disease

Table 3

SNPs located in differential methylation CpG sites from EWAS in BD.

Target_ID	P.Value	Beta.Difference	ADDRESSA_ID	CHR	UCSC_REFGENE_NAME	Functional region	CpG-SNP	MAF
cg10181180	3.65E-13	-0.033524043	39741415	2		Promoter	rs10454134	0.230
cg15835500	3.61E-12	-0.035509286	51694401	6		CTCF-binding	rs176249	0.276
cg12480843	1.8E-11	-0.037228341	23659445	8	UBE2W	TSS200;TSS200	rs3808620	0.184
cg08338478	1.3E-10	-0.042262334	10617308	2	HECW2	Enhancer	rs10176517	0.162
cg00062736	3.55E-10	-0.086936418	63727392	15	MEF2A	Enhancer	rs11247118	0.392
cg23296792	0.000000856	-0.175644181	72682370	5	FBXO38	Enhancer	rs78016579	0.135
cg03157605	0.000000902	-0.028707179	53675427	6	MDC1	1stExon;5′UTR	rs9461624	0.059
cg16744961	0.000103889	-0.061269519	60757411	12	CLECL1	TSS200	rs10492166	0.424
cg26824678	0.002223998	-0.155996614	49786417	1	CAPZB	Promoter	rs34929465	0.258
cg00254095	0.004197255	-0.141190315	69780487	18	RPL17;SNORD58C;U58	TSS1500	rs6507921	0.478

a: CHR = Chromosome containing the CpG;
b: UCSC_REFGENE_NAME = Target gene name(s), from the UCSC database;
c: MAF = Minor allele frequency of SNP(s);
d: TSS = transcription start site;
e: UTR = untranslated region