Visceral Leishmaniasis Treatment Outcome and Associated Factors in Northern Ethiopia

Table 3

Multivariable logistic regression analysis of predictors of poor treatment outcome among VL patients at ACSH, Tigray Region, Northern Ethiopia, June 2016–April 2018.

Variables	Category	Treatment outcome		COR (95% CI)	P- value	AOR (95% CI)	P -Value
		Good, n (%)	Poor, n (%)
Age in years	18-35	84(64.6)	10(55.6)	1		1
	36-50	37(28.5)	5(27.8)	1.14(0.36, 3.55)	0.83	0.83(0.22, 3.20)	0.78
	>50	9(6.9)	3(16.7)	2.8(0.65,12.08)	0.17	4.80(0.87, 26.46)	0.07
Duration prior to diagnosis (weeks)	<2	39(30)	3(16.7)	1		1
	2-4	50(38.5)	2(11.1)	0.52(0.83, 3.23)	0.48	0.56(0.07, 4.25)	0.58
	>4	41(31.5)	13(72.2)	4.12(1.09, 15.58)	0.04	6.08(1.29, 28.55)	0.02
Body weakness	No	19(14.6)	5(27.8)	1		1
	Yes	111(85.4)	13(72.2)	0.44(0.14, 1.39)	0.164	0.69(0.18, 2.68)	0.59
Epistaxis	No	112(86.2)	14(77.8)	1		1
	Yes	18(13.8)	4(22.2)	2.39(0.76, 7.52)	0.135	3.22(0.73, 14. 31)	0.12
TB	No	104(80)	8(44.4)	1		1
	Yes	26(20)	10(55.6)	5 (1.80, 13.92)	0.002	4.55 (1.08, 19.13)	0.04
HIV Status	No	105(80.8)	12(66.7)	1		1
	Yes	25(19.2)	6(33.3)	2.10(0.72, 6.12)	0.17	1.29(0.12, 14.56)	0.83
Malaria	No	97(74.6)	11(61.1)	1		1
	Yes	33(25.4)	7(38.9)	1.87(0.67, 5.22)	0.23	2.30(0.63, 8.43)	0.21
TB/HIV coinfection	No	120 (92.3)	13 (72.2)	1		1
	Yes	10 (7.7)	5 (27.8)	4.62(1.37, 15.58)	0.014	2.68(0.14, 50.64)	0.51

AOR: adjusted odds ratio, CI: confidence interval, and HIV: human immune deficiency virus.