Effect of Immunomodulatory Supplements Based on Echinacea Angustifolia and Echinacea Purpurea on the Posttreatment Relapse Incidence of Genital Condylomatosis: A Prospective Randomized Study
Table 2
Posttreatment relapse incidence of genital condylomatosis stratified for age, gender, and grade.
Group A N = 64 N (%)
Group B N = 61 N(%)
P value1
1-month follow-up
Total group
Negative
54 (84.4)
36 (59.0)
<.01
Positive
10 (15.6)
25 (41.0)
Age (years)
≤ 25
Negative
6 (66.7)
3 (42.9)
NS
Positive
3 (33.3)
4 (57.1)
> 25
Negative
48 (87.3)
33 (61.1)
<.01
Positive
7 (12.7)
21 (38.9)
Gender
Females
Negative
42 (87.5)
29 (69.0)
<.05
Positive
6 (12.5)
13 (31.0)
Males
Negative
12 (75.0)
7 (36.8)
<.05
Positive
4 (25.0)
12 (63.2)
Grade2
1
Negative
34 (91.9)
25 (75.8)
NS
Positive
3 (8.1)
8 (24.2)
2
Negative
17 (77.3)
11 (50.0)
NS
Positive
5 (22.7)
11 (50.0)
3
Negative
3 (60.0)
0 (0)
<.05
Positive
2 (40.0)
6 (100)
6-month follow-up
Total
Negative
56 (87.5)
37 (60.7)
<.001
Positive
8 (12.5)
24 (39.3)
Age (years)
≤ 25
Negative
7 (77.8)
4 (57.1)
NS
Positive
2 (22.2)
3 (42.9)
> 25
Negative
49 (89.1)
33 (61.1)
<.001
Positive
6 (10.9)
21 (38.9)
Gender
Females
Negative
43 (89.6)
30 (71.4)
<.05
Positive
5 (10.4)
12 (28.6)
Males
Negative
13 (81.2)
7 (36.8)
<.05
Positive
3 (18.8)
12 (63.2)
Grade2
1
Negative
35 (94.6)
25 (75.8)
<.05
Positive
2 (5.4)
8 (24.2)
2
Negative
17 (77.3)
11 (50.0)
NS
Positive
5 (22.7)
11 (50.0)
3
Negative
4 (80.0)
1 (16.7)
<.05
Positive
1 (20.0)
5 (83.3)
12-month follow-up
Total
Negative
61 (95.3)
44 (72.1)
<.0001
Positive
3 (4.7)
17 (27.9)
Age (years)
≤ 25
Negative
9 (100.0)
5 (71.4)
NS
Positive
0 (0)
2 (28.6)
> 25
Negative
52 (94.5)
39 (72.2)
<.005
Positive
3 (5.5)
15 (27.8)
Gender
Females
Negative
45 (93.8)
32 (76.2)
<.05
Positive
3 (6.2)
10 (23.8)
<.05
Males
Negative
16 (100)
12 (63.2)
Positive
0 (0)
7 (36.8)
Grade2
1
Negative
37 (100)
29 (87.9)
<.05
Positive
0 (0)
4 (12.1)
2
Negative
19 (86.4)
14 (63.6)
NS
Positive
3 (13.6)
8 (36.4)
3
Negative
5 (100)
1 (16.7)
<.05
Positive
0 (0)
5 (83.3)
test. 2Patients were classified into 3 lesion degrees, according to the number of genital areas affected by condylomas and the number of the condylomas: from 1 to 5 condylomas on 1-2 genital areas (mild and localized condylomatosis); > 5 condylomas on 2-3 genital areas (mild and diffuse condylomatosis); and > 5 condylomas on > 3 genital areas (extended condylomatosis).
