Clinical Study
Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia
Table 1
Demographic characteristic of the participants.
| Parameter | Control n = 25 | NS oil n = 27 | value |
| Age (years) (mean ± SD) | 37.2 ± 14.4 | 33.8 ± 13.9 | 0.38 |
| Age ranges (years), n (%) | <25 | 5 (20) | 9 (33.3) | | 25–34 | 8 (32) | 9 (33.3) | | 35–44 | 5 (20) | 2 (7.4) | | ≥45 | 7 (28) | 7 (26.0) | 0.52 |
| Gender, n (%) | Male | 11 (44) | 16 (59.3) | | Female | 14 (56) | 11 (40.7) | 0.27 |
| BMI, n (%) | Normal | 11 (44) | 13 (48.1) | | Overweight | 6 (24) | 5 (18.5) | | Obese | 8 (32) | 9 (33.3) | 0.89 |
| Smoking habit, n (%) | No | 18 (72) | 21 (77.8) | | Yes | 7 (28) | 6 (22.2) | 0.63 |
| Family history, n (%) | Negative | 22 (88) | 24 (88.9) | | Positive | 3 (12) | 3 (11.1) | |
| Dental status, n (%) | Good | 5 (24) | 5 (18.5) | | Fair | 12 (48) | 16 (59.3) | | Bad | 7 (28) | 6 (22.2) | 0.72 |
| Salivary IL-6 (pg/ml) (mean ± SD) | 159.8 ± 57.7 | 106.7 ± 47.2 | 0.52 | Salivary TNF-α (pg/ml) (mean ± SD) | 56.8 ± 24.8 | 38.3 ± 14.1 | 0.51 |
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AML, acute myeloid leukemia; BMI, body mass index; NS, Nigella sativa.
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