Clinical Study

Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia

Table 1

Demographic characteristic of the participants.

ParameterControl n = 25NS oil n = 27 value

Age (years) (mean ± SD)37.2 ± 14.433.8 ± 13.90.38

Age ranges (years), n (%)
 <255 (20)9 (33.3)
 25–348 (32)9 (33.3)
 35–445 (20)2 (7.4)
 ≥457 (28)7 (26.0)0.52

Gender, n (%)
 Male11 (44)16 (59.3)
 Female14 (56)11 (40.7)0.27

BMI, n (%)
 Normal11 (44)13 (48.1)
 Overweight6 (24)5 (18.5)
 Obese8 (32)9 (33.3)0.89

Smoking habit, n (%)
 No18 (72)21 (77.8)
 Yes7 (28)6 (22.2)0.63

Family history, n (%)
 Negative22 (88)24 (88.9)
 Positive3 (12)3 (11.1)

Dental status, n (%)
 Good5 (24)5 (18.5)
 Fair12 (48)16 (59.3)
 Bad7 (28)6 (22.2)0.72

Salivary IL-6 (pg/ml) (mean ± SD)159.8 ± 57.7106.7 ± 47.20.52
Salivary TNF-α (pg/ml) (mean ± SD)56.8 ± 24.838.3 ± 14.10.51

AML, acute myeloid leukemia; BMI, body mass index; NS, Nigella sativa.