Comparison of Preoperative Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Bladder Cancer Patients Undergoing Radical Cystectomy

Table 2

Univariate and multivariate analyses of factors associated with OS in bladder cancer patients undergoing radical cystectomy.

Variable	Univariate		Multivariate
	HR (95% CI range)	value	HR (95% CI range)	value
Age	1.023 (1.001–1.046)	0.046
Gender	1.055 (0.557–1.997)	0.869
CCI	1.145 (0.904–1.451)	0.262
Grade	1.853 (0.666–5.151)	0.237
LVI	0.510 (0.320–0.813)	0.005
Adjuvant chemotherapy	1.436 (0.828–2.489)	0.197
Hydronephrosis	2.802 (1.792–4.381)	<0.001
T stage	1.751 (1.440–2.130)	<0.001	1.531 (1.188–1.972)	0.001
N Stage	3.774 (2.303–6.186)	<0.001	2.888 (1.476–5.650)	0.002
NLR	1.643 (1.044–2.585)	0.032
PLR	1.983 (1.262–3.116)	0.003	1.730 (1.010–2.964)	0.046

HR: hazard ratio; CCI: Charlson comorbidity index; LVI: lymphovascular invasion; CIS: carcinoma in situ; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio.