Integration of Gene Expression Profile Data to Verify Hub Genes of Patients with Stanford A Aortic Dissection

Table 2

The significant enriched analysis of differentially expressed genes in thoracic aortic dissection.

Expression	Category	Term	Description	Gene Count	P-Value
DOWN-DEGs	BP	response to unfolded protein	GO:0006986	4	5.03E-03
	BP	positive regulation of glycogen biosynthetic process	GO:0045725	3	6.66E-03
	BP	positive regulation of transcription, DNA-templated	GO:0045893	11	1.06E-02
	BP	vesicle organization	GO:0016050	3	2.23E-02
	BP	sarcomere organization	GO:0045214	3	2.39E-02
	CC	Z disc	GO:0030018	7	3.24E-04
	CC	focal adhesion	GO:0005925	11	9.94E-04
	CC	stress fiber	GO:0001725	4	8.61E-03
	CC	cytoskeleton	GO:0005856	8	2.63E-02
	CC	actin cytoskeleton	GO:0015629	6	2.81E-02
	MF	actin binding	GO:0003779	10	2.70E-04
	MF	structural constituent of muscle	GO:0008307	4	3.94E-03
	MF	phosphatidylserine binding	GO:0001786	3	3.20E-02
	MF	receptor tyrosine kinase binding	GO:0030971	3	4.21E-02
	MF	calcium ion binding	GO:0005509	11	4.61E-02
UP-DEGs	BP	DNA recombination	GO:0006310	5	1.93E-04
	BP	base-excision repair	GO:0006284	5	6.20E-04
	BP	positive regulation of DNA-directed DNA polymerase activity	GO:1900264	3	3.99E-03
	BP	DNA replication initiation	GO:0006270	4	4.91E-03
	BP	DNA repair	GO:0006281	6	5.88E-03
	CC	extracellular exosome	GO:0070062	53	7.40E-04
	CC	spindle microtubule	GO:0005876	5	1.65E-03
	CC	Ctf18 RFC-like complex	GO:0031390	3	3.71E-03
	CC	membrane	GO:0016020	25	4.31E-03
	CC	cytoplasm	GO:0005737	54	2.68E-02
	MF	ATP binding	GO:0005524	35	4.75E-04
	MF	DNA clamp loader activity	GO:0003689	3	7.05E-03
	MF	single-stranded DNA-dependent ATPase activity	GO:0043142	3	8.97E-03
	MF	purine nucleobase binding	GO:0002060	2	3.26E-02
	MF	protein-tyrosine sulfotransferase activity	GO:0008476	2	3.26E-02