Clinicopathologic and Prognostic Significance of Body Mass Index (BMI) among Breast Cancer Patients in Western China: A Retrospective Multicenter Cohort Based on Western China Clinical Cooperation Group (WCCCG)
Table 1
Demographics for eligible patients according to BMI (n=8,394).
Characteristics
BMI (kg/m2) (%)
P
<18.5
18.5-24.9
≥25
Total
Menopausal status
Premenopausal
225(54.7)
3,177(56.5)
1060 (44.9)
4,462(53.2)
<0.001
Postmenopausal
186(45.3)
2,444(43.5)
1302(55.1)
3,932(46.8)
Age at diagnosis (years)
Mean ± SD
48.5±13.7
49.1±11.1
52.6±10.7
50.0±11.2
<0.00
Marital status
Married
389(94.6)
5494(97.7)
2321(98.3)
8204(97.7)
<0.001
Single/widowed/divorced
22 (5.4)
120(2.1)
35(1.5)
177(2.1)
Missing data
0 (0)
7(0.1)
6(0.3)
13(0.2)
Age at menarche (years)
9-12
45(10.9)
693(12.3)
320(13.5)
1058(12.6)
0.02
13-15
271(65.9)
3754(66.8)
1480(62.7)
5505(65.6)
16-18
89(21.7)
1058(18.8)
512(21.7)
1659(19.8)
>18
6(1.5)
112(2.0)
44(1.9)
162(1.9)
Missing data
0(0)
4(0.1)
6(0.3)
10(0.1)
No. of pregnancies
0
80(19.5)
1203(21.4)
479(20.3)
1762(21.0)
<0.001
1
100(24.3)
1523(27.1)
481(20.4)
2104(25.1)
2
105(25.5)
1147(20.4)
522(22.1)
1774(21.1)
3
51(12.4)
854(15.2)
357(15.1)
1262(15.0)
4
40(9.7)
496(8.8)
248(10.5)
784(9.3)
≥5
34(8.3)
388(6.9)
270(11.4)
692(8.2)
Missing data
1(0.2)
10(0.2)
5(0.2)
16(0.2)
No. of births
0
82(20.0)
1114(19.8)
418(17.7)
1614(19.2)
<0.001
1
183(44.5)
2722(48.4)
876(37.1)
3781(45.0)
2
95(23.1)
1126(20.0)
602(25.5)
1823(21.7)
3
24(5.8)
405(7.2)
245(10.4)
674(8.0)
4
18(4.4)
156(2.8)
136(5.8)
310(3.7)
≥5
8(1.9)
88(1.6)
83(3.5)
179(2.1)
Missing data
1(0.2)
10(0.2)
2(0.1)
13(0.2)
Laterality
Left
204(49.6)
2867(51.0)
1222(51.7)
4293(51.1)
0.9
Right
195(47.4)
2640(47.0)
1107(46.9)
3942(47.0)
Bilateral
4(1.0)
44(0.8)
15(0.6)
63(0.8)
Missing data
8(1.9)
70(1.2)
18(0.8)
96(1.1)
Multifocality
No
402(97.8)
5453(97.0)
2313(97.9)
8168(97.3)
0.06
Yes
9(2.2)
168(3.0)
49(2.1)
226(2.7)
Initial symptoms and signs
Breast lump
349(84.9)
4788(85.2)
1962(83.1)
7099(84.6)
0.00
Breast pain
24(5.8)
468(8.3)
215(9.1)
707(8.4)
Nipple discharge
13(3.2)
108(1.9)
50(2.1)
171(2.0)
Nipple inversion
4(1.0)
60(1.1)
48(2.0)
112(1.3)
Missing data
21(5.1)
197(3.5)
87(3.7)
305(3.6)
Tumor size (cm)
≤ 1 cm
8(1.9)
136(2.4)
36(1.5)
180(2.1)
<0.001
1>, ≤ 2 cm
74(18.0)
879(15.6)
264(11.2)
1217(14.5)
2>, ≤ 5 cm
198(48.2)
2954(52.6)
1322(56.0)
4474(53.3)
>5 cm
41(10.0)
585(10.4)
327(13.8)
953(11.4)
Missing data
90(21.9)
1067(19.0)
413(17.5)
1570(18.7)
Distant metastasis
No
397(96.6)
5464(97.2)
2278(96.4)
8139(97.0)
0.51
Yes
11(2.7)
105(1.9)
44(1.9)
160(1.9)
Missing data
3(0.7)
52(0.9)
40(1.7)
95(1.1)
Pearson χ2 test, except Student’s t-test and Fisher’s exact test.
