Naringin Reverses High-Cholesterol Diet-Induced Vascular Dysfunction and Oxidative Stress in Rats via Regulating LOX-1 and NADPH Oxidase Subunit Expression

Table 1

The parameters at the end of the experiment of control and hypercholesterolaemic rats with or without naringin treatment.

Parameter	C	HC	HCN	CN
Initial body weight (g)	195 ± 2	196 ± 7	195 ± 10	218 ± 1
Final body weight (g)	432 ± 5	479 ± 4	428 ± 9^##	424 ± 12^##
Serum TC (mg/dl)	67 ± 5	346 ± 17	164 ± 14^,##	67 ± 1^##
Serum TG (mg/dl)	39 ± 6	82 ± 5	48 ± 5^#	38 ± 2^#
Serum LDL-C (mg/dl)	28 ± 7	293 ± 8	113 ± 11^,##	22 ± 2^##
Serum HDL-C (mg/dl)	42 ± 1	25 ± 4	43 ± 3^##	37 ± 2^#
AC	0.75 ± 0.32	9.62 ± 1.82	4.69 ± 0.57^,##	0.81 ± 0.10^###
CRR	1.75 ± 0.32	10.62 ± 1.81	5.69 ± 0.57^,##	1.81 ± 0.10^###
AIP	0.01 ± 0.08	0.59 ± 0.15	0.30 ± 0.06^,#	0.02 ± 0.03^##

Results are shown as mean ± SEM for 8–10 rats. , , and vs. C group; , , and vs. HC group. TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; AC, atherogenic coefficient; CRR, cardiac risk ratio; AIP, atherogenic index of plasma.