Identifying Protein Complexes from Dynamic Temporal Interval Protein-Protein Interaction Networks

Table 7

Statistical matching-based metrics of the complexes identified by five competing methods.

Yeast expression data sets	Yeast PPI data sets	Methods	#PM	fm	Frac	Acc	MMR	FAM	#PM×FAM
GSE3431	STRING	ICJointLE-DPN	190	0.71	0.95	0.75	0.75	2.45	465.50
		Zhang’s method	92	0.63	0.86	0.80	0.59	2.25	207.00
		DPC-NADPIN	34	0.71	0.77	0.71	0.48	1.96	66.64
		TS-OCD	20	0.55	0.46	0.68	0.30	1.45	29.00
		DCA	7	0.55	0.51	0.57	0.27	1.35	9.45
	BioGrid	ICJointLE-DPN	185	0.72	0.93	0.80	0.73	2.46	455.10
		Zhang’s method	98	0.63	0.85	0.78	0.58	2.21	216.58
		DPC-NADPIN	39	0.71	0.75	0.72	0.48	1.94	75.66
		TS-OCD	41	0.66	0.65	0.73	0.43	1.81	74.21
		DCA	8	0.55	0.51	0.56	0.27	1.34	10.72
	DIP	ICJointLE-DPN	174	0.69	0.85	0.70	0.68	2.23	388.02
		Zhang’s method	94	0.67	0.76	0.71	0.52	1.99	187.06
		DPC-NADPIN	23	0.63	0.55	0.67	0.35	1.57	36.11
		TS-OCD	12	0.39	0.27	0.54	0.18	1.00	12.00
		DCA	9	0.48	0.36	0.55	0.21	1.12	10.08
GSE4987	STRING	ICJointLE-DPN	185	0.60	0.95	0.72	0.75	2.42	447.70
		Zhang’s method	97	0.64	0.91	0.79	0.62	2.32	225.04
		DPC-NADPIN	6	0.52	0.56	0.59	0.30	1.46	8.76
		TS-OCD	15	0.55	0.53	0.68	0.34	1.56	23.4
		DCA	6	0.61	0.70	0.64	0.37	1.71	10.26
	BioGrid	ICJointLE-DPN	187	0.67	0.93	0.76	0.74	2.43	454.41
		Zhang’s method	104	0.63	0.90	0.78	0.63	2.31	240.24
		DPC-NADPIN	8	0.54	0.55	0.60	0.13	1.45	11.6
		TS-OCD	39	0.66	0.68	0.74	0.46	1.88	73.32
		DCA	9	0.62	0.68	0.65	0.36	1.69	15.17
	DIP	ICJointLE-DPN	174	0.67	0.86	0.68	0.68	2.22	386.28
		Zhang’s method	106	0.67	0.83	0.74	0.58	2.15	227.9
		DPC-NADPIN	6	0.44	0.36	0.53	0.21	1.10	6.60
		TS-OCD	16	0.41	0.29	0.54	0.20	1.04	16.64
		DCA	11	0.58	0.50	0.63	0.29	1.42	15.62