Table 1: Functional enrichment analysis of upregulated genes in the old mouse ovarian secondary follicles compared to young mouse.

CategoryTermCount%P Value

GOTERM_BP_DIRECTGO:0035458~cellular response to interferon-beta158.65.62E-21
GOTERM_BP_DIRECTGO:0009615~response to virus1810.36.73E-21
GOTERM_BP_DIRECTGO:0051607~defense response to virus2112.11.15E-19
GOTERM_BP_DIRECTGO:0002376~immune system process2413.81.01E-15
GOTERM_BP_DIRECTGO:0045087~innate immune response2313.22.70E-14
GOTERM_BP_DIRECTGO:0071346~cellular response to interferon-gamma95.21.80E-08
GOTERM_BP_DIRECTGO:0042832~defense response to protozoan63.41.60E-06
GOTERM_BP_DIRECTGO:0006952~defense response84.61.36E-05
GOTERM_BP_DIRECTGO:0032870~cellular response to hormone stimulus63.41.57E-05
GOTERM_BP_DIRECTGO:0034097~response to cytokine74.01.79E-05
GOTERM_CC_DIRECTGO:0020005~symbiont-containing vacuole membrane52.91.46E-07
GOTERM_CC_DIRECTGO:0005829~cytosol2816.17.00E-05
GOTERM_CC_DIRECTGO:0005737~cytoplasm6537.46.61E-04
GOTERM_CC_DIRECTGO:0005634~nucleus5833.32.75E-03
GOTERM_CC_DIRECTGO:0048471~perinuclear region of cytoplasm126.98.23E-03
GOTERM_CC_DIRECTGO:0072562~blood microparticle52.91.34E-02
GOTERM_CC_DIRECTGO:0031225~anchored component of membrane52.91.63E-02
GOTERM_CC_DIRECTGO:0009897~external side of plasma membrane74.02.23E-02
GOTERM_MF_DIRECTGO:0003725~double-stranded RNA binding95.22.62E-08
GOTERM_MF_DIRECTGO:0003690~double-stranded DNA binding116.33.33E-08
GOTERM_MF_DIRECTGO:0003924~GTPase activity116.31.81E-06
GOTERM_MF_DIRECTGO:0005525~GTP binding126.96.76E-05
GOTERM_MF_DIRECTGO:0008134~transcription factor binding105.75.97E-04
GOTERM_MF_DIRECTGO:0003723~RNA binding158.69.40E-04
GOTERM_MF_DIRECTGO:0003677~DNA binding2514.41.58E-03
GOTERM_MF_DIRECTGO:0001730~2′-5′-oligoadenylate synthetase activity31.72.48E-03
GOTERM_MF_DIRECTGO:0016817~hydrolase activity, acting on acid anhydrides31.72.48E-03
GOTERM_MF_DIRECTGO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding84.62.65E-03

of enriched genes in each term. The top ten terms based on P value were chosen in each category.